人 ANXA8 (NM_001271703) cDNA克隆

Accession: NM_001271703
基因名称: ANXA8
基因别名: ANX8
基因描述: Homo sapiens annexin A8 (ANXA8), transcript variant 3, mRNA.
种属: Human
CDS区长度: 798 (查看编码区序列)
翻译后氨基酸长度: 265 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks exons in the 5' coding region compared to variant 1. It encodes isoform 3, which is shorter when compared to isoform 1. An in-frame AUG is located 66 codons upstream of the annotated translation start site but was not annotated as a start site since it is not conserved and is in a weak Kozak sequence context.
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G120619 人 ANXA8 (NM_001271703) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin-specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10. [provided by RefSeq, Jul 2008]