人 SEMA5B (NM_001256346) cDNA克隆

Accession: NM_001256346
基因名称: SEMA5B
基因别名: SemG; SEMAG
基因描述: Homo sapiens sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B (SEMA5B), transcript variant 2, mRNA.
种属: Human
CDS区长度: 3456 (查看编码区序列)
翻译后氨基酸长度: 1151 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein (isoform 1).
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G120721 人 SEMA5B (NM_001256346) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the semaphorin protein family which regulates axon growth during development of the nervous system. The encoded protein has a characteristic Sema domain near the N-terminus, through which semaphorins bind to plexin, and five thrombospondin type 1 repeats in the C-terminal region of the protein. The protein product may be cleaved and exist as a secreted molecule (PMID: 19463192). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]