人 SEMA5B (NM_001256348) cDNA克隆

基本信息

Accession: NM_001256348
基因名称: SEMA5B
基因别名: SemG; SEMAG
基因描述: Homo sapiens sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B (SEMA5B), transcript variant 4, mRNA.
种属: Human
CDS区长度: 3174 (查看编码区序列)
翻译后氨基酸长度: 1057 (查看氨基酸序列)
Transcript Variant: This variant (4) lacks an alternate in-frame exon in the 5' coding region, uses a downstream start codon and uses an alternate in-frame splice site in the 3' coding region compared to variant 1. The resulting protein (isoform 3) is shorter and has a shorter N-terminus compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G120723 人 SEMA5B (NM_001256348) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SEMA5B (NM_001031702) cDNA克隆 transcript variant 1
人 SEMA5B (NM_001256346) cDNA克隆 transcript variant 2
人 SEMA5B (NM_001256347) cDNA克隆 transcript variant 3
人 SEMA5B (NM_001256348) cDNA克隆 transcript variant 4

基因简介

This gene encodes a member of the semaphorin protein family which regulates axon growth during development of the nervous system. The encoded protein has a characteristic Sema domain near the N-terminus, through which semaphorins bind to plexin, and five thrombospondin type 1 repeats in the C-terminal region of the protein. The protein product may be cleaved and exist as a secreted molecule (PMID: 19463192). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

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