人 HIF3A (NM_152794) cDNA克隆

Accession: NM_152794
基因名称: HIF3A
基因别名: IPAS; MOP7; PASD7; HIF-3A; bHLHe17
基因描述: Homo sapiens hypoxia inducible factor 3, alpha subunit (HIF3A), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2004 (查看编码区序列)
翻译后氨基酸长度: 667 (查看氨基酸序列)
Transcript Variant: This variant (1) differs in the 5' UTR and 5' coding region, compared to variant 3. The resulting isoform (a) has a distinct and shorter N-terminus, compared to isoform c.
产品编号 产品名称 载体 规格 价格
G120801 人 HIF3A (NM_152794) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]