人 HIF3A (NM_152796) cDNA克隆

Accession: NM_152796
基因名称: HIF3A
基因别名: IPAS; MOP7; PASD7; HIF-3A; bHLHe17
基因描述: Homo sapiens hypoxia inducible factor 3, alpha subunit (HIF3A), transcript variant 4, mRNA.
种属: Human
CDS区长度: 1353 (查看编码区序列)
翻译后氨基酸长度: 450 (查看氨基酸序列)
Transcript Variant: This variant (4) differs in the 5' UTR and 5' coding region, uses an alternate start codon, and differs in the 3' coding region and 3' UTR, compared to variant 3. The resulting isoform (d) has distinct N- and C-termini, and is shorter than isoform c.
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G120803 人 HIF3A (NM_152796) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]