人 IFT122 (NM_001280541) cDNA克隆

Accession: NM_001280541
基因名称: IFT122
基因别名: CED; SPG; CED1; WDR10; WDR10p; WDR140
基因描述: Homo sapiens intraflagellar transport 122 homolog (Chlamydomonas) (IFT122), transcript variant 5, mRNA.
种属: Human
CDS区长度: 3705 (查看编码区序列)
翻译后氨基酸长度: 1234 (查看氨基酸序列)
Transcript Variant: This variant (5) lacks an alternate in-frame exon in the 5' coding region and uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. It encodes isoform 5, which is shorter than isoform 1.
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G121222 人 IFT122 (NM_001280541) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This cytoplasmic protein contains seven WD repeats and an AF-2 domain which function by recruiting coregulatory molecules and in transcriptional activation. Mutations in this gene cause cranioectodermal dysplasia-1. A related pseudogene is located on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]