人 NTRK2 (NM_006180) cDNA克隆

基本信息

Accession: NM_006180
基因名称: NTRK2
基因别名: TRKB; trk-B; GP145-TrkB
基因描述: Homo sapiens neurotrophic tyrosine kinase, receptor, type 2 (NTRK2), transcript variant a, mRNA.
种属: Human
CDS区长度: 2517 (查看编码区序列)
翻译后氨基酸长度: 838 (查看氨基酸序列)
Transcript Variant: This variant (a; also known as TrkB) encodes the full-length protein that includes the tyrosine kinase catalytic domain. This is the longest isoform (a).

订购信息

产品编号 产品名称 载体 规格 价格
G121383 人 NTRK2 (NM_006180) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 NTRK2 (NM_006180) cDNA克隆 transcript variant a
人 NTRK2 (NM_001007097) cDNA克隆 transcript variant b
人 NTRK2 (NM_001018064) cDNA克隆 transcript variant c
人 NTRK2 (NM_001018065) cDNA克隆 transcript variant d
人 NTRK2 (NM_001018066) cDNA克隆 transcript variant e

基因简介

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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