人 MCL1 (NM_182763) cDNA克隆

基本信息

Accession: NM_182763
基因名称: MCL1
基因别名: TM; EAT; MCL1L; MCL1S; Mcl-1; BCL2L3; MCL1-ES; bcl2-L-3; mcl1/EAT
基因描述: Homo sapiens myeloid cell leukemia sequence 1 (BCL2-related) (MCL1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 816 (查看编码区序列)
翻译后氨基酸长度: 271 (查看氨基酸序列)
Transcript Variant: This variant (2), also known as MCL-1S (short), lacks an alternate exon that causes a frameshift, compared to variant 1. The resulting protein (isoform 2) has a distinct C-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G121565 人 MCL1 (NM_182763) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 MCL1 (NM_001197320) cDNA克隆 transcript variant 3
人 MCL1 (NM_021960) cDNA克隆 transcript variant 1
人 MCL1 (NM_182763) cDNA克隆 transcript variant 2

基因简介

This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010]

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