人 MCL1 (NM_001197320) cDNA克隆

Accession: NM_001197320
基因名称: MCL1
基因别名: TM; EAT; MCL1L; MCL1S; Mcl-1; BCL2L3; MCL1-ES; bcl2-L-3; mcl1/EAT
基因描述: Homo sapiens myeloid cell leukemia 1 (MCL1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 594 (查看编码区序列)
翻译后氨基酸长度: 197 (查看氨基酸序列)
Transcript Variant: This variant (3), also known as MCL-1ES (extra short), uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. This results in a shorter protein (isoform 3), compared to isoform 1.
产品编号 产品名称 载体 规格 价格
G121566 人 MCL1 (NM_001197320) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010]