人 SEPT7 (NM_001788) cDNA克隆

Accession: NM_001788
基因名称: SEPT7
基因别名: CDC3; CDC10; SEPT7A; NBLA02942
基因描述: Homo sapiens septin 7 (SEPT7), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1314 (查看编码区序列)
翻译后氨基酸长度: 437 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
产品编号 产品名称 载体 规格 价格
G121898 人 SEPT7 (NM_001788) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19. [provided by RefSeq, Jul 2011]