人 AKR1D1 (NM_001190907) cDNA克隆

基本信息

Accession: NM_001190907
基因名称: AKR1D1
基因别名: CBAS2; SRD5B1; 3o5bred
基因描述: Homo sapiens aldo-keto reductase family 1, member D1 (AKR1D1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 873 (查看编码区序列)
翻译后氨基酸长度: 290 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an alternate exon compared to variant 1, that causes a frameshift. The resulting isoform (3) has a shorter and distinct C-terminus compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G121911 人 AKR1D1 (NM_001190907) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 AKR1D1 (NM_005989) cDNA克隆 transcript variant 1
人 AKR1D1 (NM_001190906) cDNA克隆 transcript variant 2
人 AKR1D1 (NM_001190907) cDNA克隆 transcript variant 3

基因简介

The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet. [provided by RefSeq, Jul 2010]

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