人 CORIN (NM_001278585) cDNA克隆

Accession: NM_001278585
基因名称: CORIN
基因别名: CRN; ATC2; Lrp4; PEE5; TMPRSS10
基因描述: Homo sapiens corin, serine peptidase (CORIN), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2817 (查看编码区序列)
翻译后氨基酸长度: 938 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks two in-frame exons in the coding region, compared to variant 1. The resulting isoform (2) lacks two internal segments, compared to isoform 1.
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G122574 人 CORIN (NM_001278585) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. The encoded protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013]