人 CORIN (NM_001278586) cDNA克隆

基本信息

Accession: NM_001278586
基因名称: CORIN
基因别名: CRN; ATC2; Lrp4; PEE5; TMPRSS10
基因描述: Homo sapiens corin, serine peptidase (CORIN), transcript variant 3, mRNA.
种属: Human
CDS区长度: 2205 (查看编码区序列)
翻译后氨基酸长度: 734 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an in-frame internal exon and multiple 3' terminal exons, and its transcription extends past a splice site that is used in variant 1, resulting in a novel 3' coding region and 3' UTR compared to variant 1. The resulting isoform (3) is shorter; it lacks an internal segment and has a distinct C-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G122575 人 CORIN (NM_001278586) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CORIN (NM_006587) cDNA克隆 transcript variant 1
人 CORIN (NM_001278585) cDNA克隆 transcript variant 2
人 CORIN (NM_001278586) cDNA克隆 transcript variant 3

基因简介

This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. The encoded protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013]

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