人 TJP3 (NM_001267561) cDNA克隆

基本信息

Accession: NM_001267561
基因名称: TJP3
基因别名: ZO3; ZO-3
基因描述: Homo sapiens tight junction protein 3 (TJP3), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2787 (查看编码区序列)
翻译后氨基酸长度: 928 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and represents use of an alternate promoter, compared to variant 1, which results in a protein (isoform 2) with a longer and distinct N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G122698 人 TJP3 (NM_001267561) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TJP3 (NM_001267560) cDNA克隆 transcript variant 1
人 TJP3 (NM_001267561) cDNA克隆 transcript variant 2

基因简介

The protein encoded by this gene is a member of the membrane-associated guanylate kinase-like (MAGUK) protein family which is characterized by members having multiple PDZ domains, a single SH3 domain, and a single guanylate kinase-like (GUK)-domain. In addition, members of the zonula occludens protein subfamily have an acidic domain, a basic arginine-rich region, and a proline-rich domain. The protein encoded by this gene plays a role in the linkage between the actin cytoskeleton and tight-junctions and also sequesters cyclin D1 at tight junctions during mitosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. This gene has a partial pseudogene on chromosome 1. [provided by RefSeq, May 2012]

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