人 ARHGAP22 (NM_001256024) cDNA克隆

Accession: NM_001256024
基因名称: ARHGAP22
基因别名: RhoGAP2; RhoGap22
基因描述: Homo sapiens Rho GTPase activating protein 22 (ARHGAP22), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2145 (查看编码区序列)
翻译后氨基酸长度: 714 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform 1).
产品编号 产品名称 载体 规格 价格
G122753 人 ARHGAP22 (NM_001256024) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins. The encoded protein is insulin-responsive, is dependent on the kinase Akt and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues. The result of these interactions is regulation of cell motility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]