人 ZNF189 (NM_197977) cDNA克隆

基本信息

Accession: NM_197977
基因名称: ZNF189
基因描述: Homo sapiens zinc finger protein 189 (ZNF189), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1755 (查看编码区序列)
翻译后氨基酸长度: 584 (查看氨基酸序列)
Transcript Variant: This variant (2) contains an alternate 5' exon and uses an alternate splice junction at the 5' end of an exon compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (2) with a shorter N-terminus compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G123087 人 ZNF189 (NM_197977) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ZNF189 (NM_003452) cDNA克隆 transcript variant 1
人 ZNF189 (NM_197977) cDNA克隆 transcript variant 2
人 ZNF189 (NM_001278231) cDNA克隆 transcript variant 3
人 ZNF189 (NM_001278232) cDNA克隆 transcript variant 4
人 ZNF189 (NM_001278240) cDNA克隆 transcript variant 5

基因简介

Kruppel-like zinc finger proteins such as ZNF189 contain a conserved stretch of 7 amino acids that connects a variable number of DNA-binding zinc finger repeats of the cys(2)his(2) (C2H2) type (summarized by Odeberg et al., 1998 [PubMed 9653648]). Approximately 30% of human Kruppel-like zinc finger proteins contain an N-terminal Kruppel-associated box (KRAB) domain. The KRAB domain consists of approximately 75 amino acids that may be subdivided into an A box, which is present in every KRAB domain and is essential for transcriptional repression, and a B box, which is not always present.[supplied by OMIM, May 2010]

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