人 ZNF189 (NM_001278240) cDNA克隆

Accession: NM_001278240
基因名称: ZNF189
基因描述: Homo sapiens zinc finger protein 189 (ZNF189), transcript variant 5, mRNA.
种属: Human
CDS区长度: 258 (查看编码区序列)
翻译后氨基酸长度: 85 (查看氨基酸序列)
Transcript Variant: This variant (5) uses an alternate splice junction at the 5' end of an exon and contains an alternate 3' exon compared to variant 1. The resulting isoform (5) has a shorter and distinct N-terminus and lacks an alternate internal segment compared to isoform 1.
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G123090 人 ZNF189 (NM_001278240) cDNA克隆 pDONR223 2ug质粒 点击询价

Kruppel-like zinc finger proteins such as ZNF189 contain a conserved stretch of 7 amino acids that connects a variable number of DNA-binding zinc finger repeats of the cys(2)his(2) (C2H2) type (summarized by Odeberg et al., 1998 [PubMed 9653648]). Approximately 30% of human Kruppel-like zinc finger proteins contain an N-terminal Kruppel-associated box (KRAB) domain. The KRAB domain consists of approximately 75 amino acids that may be subdivided into an A box, which is present in every KRAB domain and is essential for transcriptional repression, and a B box, which is not always present.[supplied by OMIM, May 2010]