人 SLAMF6 (NM_001184716) cDNA克隆

基本信息

Accession: NM_001184716
基因名称: SLAMF6
基因别名: KALI; NTBA; CD352; KALIb; Ly108; NTB-A; SF2000
基因描述: Homo sapiens SLAM family member 6 (SLAMF6), transcript variant 4, mRNA.
种属: Human
CDS区长度: 666 (查看编码区序列)
翻译后氨基酸长度: 221 (查看氨基酸序列)
Transcript Variant: This variant (4) lacks an alternate exon in the 5' coding region, compared to variant 1, which result in an isoform (4) with a shorter extracellular domain than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G124210 人 SLAMF6 (NM_001184716) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SLAMF6 (NM_001184714) cDNA克隆 transcript variant 1
人 SLAMF6 (NM_052931) cDNA克隆 transcript variant 2
人 SLAMF6 (NM_001184715) cDNA克隆 transcript variant 3
人 SLAMF6 (NM_001184716) cDNA克隆 transcript variant 4

基因简介

The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, May 2010]

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