人 SLAMF6 (NM_052931) cDNA克隆

基本信息

Accession: NM_052931
基因名称: SLAMF6
基因别名: KALI; NTBA; CD352; KALIb; Ly108; NTB-A; SF2000
基因描述: Homo sapiens SLAM family member 6 (SLAMF6), transcript variant 2, mRNA.
种属: Human
CDS区长度: 996 (查看编码区序列)
翻译后氨基酸长度: 331 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region, compared to variant 1, which results in an isoform (2) that is one amino acid shorter than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G124211 人 SLAMF6 (NM_052931) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SLAMF6 (NM_001184714) cDNA克隆 transcript variant 1
人 SLAMF6 (NM_052931) cDNA克隆 transcript variant 2
人 SLAMF6 (NM_001184715) cDNA克隆 transcript variant 3
人 SLAMF6 (NM_001184716) cDNA克隆 transcript variant 4

基因简介

The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, May 2010]

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