人 SPRY4 (NM_001127496) cDNA克隆

基本信息

Accession: NM_001127496
基因名称: SPRY4
基因别名: HH17
基因描述: Homo sapiens sprouty homolog 4 (Drosophila) (SPRY4), transcript variant 2, mRNA.
种属: Human
CDS区长度: 900 (查看编码区序列)
翻译后氨基酸长度: 299 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate in-frame segment in the 5' coding region, compared to variant 1. The resulting protein (isoform 2) has a shorter N-terminus when it is compared to isoform 2.

订购信息

产品编号 产品名称 载体 规格 价格
G124216 人 SPRY4 (NM_001127496) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SPRY4 (NM_030964) cDNA克隆 transcript variant 1
人 SPRY4 (NM_001127496) cDNA克隆 transcript variant 2

基因简介

SPRY4 is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. It is positioned upstream of RAS (see HRAS; MIM 190020) activation and impairs the formation of active GTP-RAS (Leeksma et al., 2002 [PubMed 12027893]).[supplied by OMIM, Mar 2008]

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