人 NLRP7 (NM_206828) cDNA克隆

Accession: NM_206828
基因名称: NLRP7
基因别名: HYDM; PAN7; NALP7; NOD12; PYPAF3; CLR19.4
基因描述: Homo sapiens NLR family, pyrin domain containing 7 (NLRP7), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2943 (查看编码区序列)
翻译后氨基酸长度: 980 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region, compared to variant 3, resulting in a shorter protein (isoform 2), compared to isoform 3.
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G124568 人 NLRP7 (NM_206828) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]