人 SLC30A8 (NM_001172814) cDNA克隆

基本信息

Accession: NM_001172814
基因名称: SLC30A8
基因别名: ZNT8; ZnT-8
基因描述: Homo sapiens solute carrier family 30 (zinc transporter), member 8 (SLC30A8), transcript variant 2, mRNA.
种属: Human
CDS区长度: 963 (查看编码区序列)
翻译后氨基酸长度: 320 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 2, 3, 4, and 5 all encode isoform b.

订购信息

产品编号 产品名称 载体 规格 价格
G125706 人 SLC30A8 (NM_001172814) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SLC30A8 (NM_173851) cDNA克隆 transcript variant 1
人 SLC30A8 (NM_001172814) cDNA克隆 transcript variant 2
人 SLC30A8 (NM_001172811) cDNA克隆 transcript variant 3
人 SLC30A8 (NM_001172813) cDNA克隆 transcript variant 4
人 SLC30A8 (NM_001172815) cDNA克隆 transcript variant 5

基因简介

The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]

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