人 SLC30A8 (NM_173851) cDNA克隆

Accession: NM_173851
基因名称: SLC30A8
基因别名: ZNT8; ZnT-8
基因描述: Homo sapiens solute carrier family 30 (zinc transporter), member 8 (SLC30A8), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1110 (查看编码区序列)
翻译后氨基酸长度: 369 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longer isoform (a).
产品编号 产品名称 载体 规格 价格
G125708 人 SLC30A8 (NM_173851) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]