人 THPO (NM_000460) cDNA克隆

Accession: NM_000460
基因名称: THPO
基因别名: ML; TPO; MGDF; MKCSF; MPLLG; THCYT1
基因描述: Homo sapiens thrombopoietin (THPO), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1062 (查看编码区序列)
翻译后氨基酸长度: 353 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
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G125719 人 THPO (NM_000460) cDNA克隆 pDONR223 2ug质粒 点击询价

Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternate splicing results in multiple transcript variants of this gene.[provided by RefSeq, Jun 2012]