人 THPO (NM_001177598) cDNA克隆

基本信息

Accession: NM_001177598
基因名称: THPO
基因别名: ML; TPO; MGDF; MKCSF; MPLLG; THCYT1
基因描述: Homo sapiens thrombopoietin (THPO), transcript variant 3, mRNA.
种属: Human
CDS区长度: 960 (查看编码区序列)
翻译后氨基酸长度: 319 (查看氨基酸序列)
Transcript Variant: This variant (3) uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 1. It encodes isoform 3, which has a shorter and distinct C-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G125721 人 THPO (NM_001177598) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 THPO (NM_000460) cDNA克隆 transcript variant 1
人 THPO (NM_001177597) cDNA克隆 transcript variant 2
人 THPO (NM_001177598) cDNA克隆 transcript variant 3

基因简介

Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternate splicing results in multiple transcript variants of this gene.[provided by RefSeq, Jun 2012]

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