小鼠 Casp8 (NM_001277926) cDNA克隆

基本信息

Accession: NM_001277926
基因名称: Casp8
基因别名: MACH; Mch5; FLICE; CASP-8
基因描述: Mus musculus caspase 8 (Casp8), transcript variant 3, mRNA.
种属: Mouse
CDS区长度: 1503 (查看编码区序列)
翻译后氨基酸长度: 500 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR and 5' coding region and uses an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct and longer N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G129369 小鼠 Casp8 (NM_001277926) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

小鼠 Casp8 (NM_009812) cDNA克隆 transcript variant 1
小鼠 Casp8 (NM_001080126) cDNA克隆 transcript variant 2
小鼠 Casp8 (NM_001277926) cDNA克隆 transcript variant 3

基因简介

This gene is part of a family of caspases, aspartate-specific cysteine proteases well studied for their involvement in immune and apoptosis signaling. This protein, an initiator of apoptotic cell death, is activated by death-inducing tumor necrosis family receptors and targets downstream effectors. In mouse deficiency of this gene can cause embryonic lethality. This protein may have a role in embryogenesis. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Apr 2013]

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