小鼠 Casp9 (NM_001277932) cDNA克隆

基本信息

Accession: NM_001277932
基因名称: Casp9
基因别名: Mch6; APAF-3; CASP-9; AI115399; AW493809; ICE-LAP6; Caspase-9
基因描述: Mus musculus caspase 9 (Casp9), transcript variant 2, mRNA.
种属: Mouse
CDS区长度: 1218 (查看编码区序列)
翻译后氨基酸长度: 405 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate exon, which results in a frameshift, compared to variant 1. The resulting protein (isoform 2) has a distinct C-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G129371 小鼠 Casp9 (NM_001277932) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

小鼠 Casp9 (NM_015733) cDNA克隆 transcript variant 1
小鼠 Casp9 (NM_001277932) cDNA克隆 transcript variant 2

基因简介

This gene is part of a family of caspases, aspartate-specific cysteine proteases well studied for their involvement in immune and apoptosis signaling. This protein, the initiator caspase, is activated after cytochrome c release from mitochondria and targets downstream effectors. In mouse, deficiency of this gene can cause perinatal lethality. This protein may have a role in normal brain development. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Apr 2013]

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