小鼠 Crem (NM_001110852) cDNA克隆

Accession: NM_001110852
基因名称: Crem
基因别名: ICER; ICERI
基因描述: Mus musculus cAMP responsive element modulator (Crem), transcript variant 8, mRNA.
种属: Mouse
CDS区长度: 375 (查看编码区序列)
翻译后氨基酸长度: 124 (查看氨基酸序列)
Transcript Variant: This variant (8) contains multiple differences in the UTRs and coding region, including a novel 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (8) contains a shorter N-terminus and a distinct C-terminus, compared to isoform 1.
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G130040 小鼠 Crem (NM_001110852) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a basic-leucine zipper domain-containing protein that localizes to gene promoters, where it binds to the cyclic AMP response element (CRE). Different protein isoforms encoded by this gene may function as either activators or repressors of transcription. Activity of this gene is important in multiple developmental processes, including spermatogenesis. Mutation of this gene causes male infertility. Alternative splicing and promoter usage result in multiple transcript variants for this gene. [provided by RefSeq, Oct 2012]