人 CRHR1 (NM_004382) cDNA克隆

Accession: NM_004382
基因名称: CRHR1
基因别名: CRF1; CRHR; CRF-R; CRFR1; CRF-R1; CRFR-1; CRH-R1; CRHR1L; CRHR1f; CRF-R-1; CRH-R-1; CRH-R1h
基因描述: Homo sapiens corticotropin releasing hormone receptor 1 (CRHR1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1248 (查看编码区序列)
翻译后氨基酸长度: 415 (查看氨基酸序列)
Transcript Variant: This variant (2), referred to as CRHR1alpha, lacks an exon in the coding region but maintains the reading frame. The encoded isoform (2) is shorter compared to isoform 1.
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G130863 人 CRHR1 (NM_004382) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants, one of which represents a read-through transcript with the neighboring gene MGC57346. [provided by RefSeq, Jan 2012]