人 CRHR2 (NM_001883) cDNA克隆

基本信息

Accession: NM_001883
基因名称: CRHR2
基因别名: CRF2; CRFR2; CRF-RB; HM-CRF
基因描述: Homo sapiens corticotropin releasing hormone receptor 2 (CRHR2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1236 (查看编码区序列)
翻译后氨基酸长度: 411 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the predominant transcript, and encodes isoform 1 (also known as alpha isoform).

订购信息

产品编号 产品名称 载体 规格 价格
G130866 人 CRHR2 (NM_001883) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CRHR2 (NM_001883) cDNA克隆 transcript variant 1
人 CRHR2 (NM_001202475) cDNA克隆 transcript variant 2
人 CRHR2 (NM_001202481) cDNA克隆 transcript variant 3
人 CRHR2 (NM_001202482) cDNA克隆 transcript variant 4
人 CRHR2 (NM_001202483) cDNA克隆 transcript variant 5

基因简介

The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jan 2011]

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