人 ADRA1A (NM_000680) cDNA克隆

Accession: NM_000680
基因名称: ADRA1A
基因别名: ADRA1C; ADRA1L1; ALPHA1AAR
基因描述: Homo sapiens adrenoceptor alpha 1A (ADRA1A), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1401 (查看编码区序列)
翻译后氨基酸长度: 466 (查看氨基酸序列)
Transcript Variant: This variant (1) is alternatively spliced in the 3' end, compared to variant 3. It encodes isoform 1, which has a longer and distinct C-terminus compared to isoform 3.
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G131878 人 ADRA1A (NM_000680) cDNA克隆 pDONR223 2ug质粒 点击询价

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq, Jul 2008]