人 NLRP6 (NM_001276700) cDNA克隆

基本信息

Accession: NM_001276700
基因名称: NLRP6
基因别名: AVR; NAVR; PAN3; NALP6; PYPAF5; CLR11.4; NAVR/AVR
基因描述: Homo sapiens NLR family, pyrin domain containing 6 (NLRP6), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2676 (查看编码区序列)
翻译后氨基酸长度: 891 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate in-frame exon at the 5' end of an exon compared to variant 1. The resulting isoform (2) lacks a single internal aa compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G133764 人 NLRP6 (NM_001276700) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 NLRP6 (NM_138329) cDNA克隆 transcript variant 1
人 NLRP6 (NM_001276700) cDNA克隆 transcript variant 2

基因简介

The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]

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