小鼠 Prkaca (NM_001277898) cDNA克隆

基本信息

Accession: NM_001277898
基因名称: Prkaca
基因别名: PKCD; Pkaca
基因描述: Mus musculus protein kinase, cAMP dependent, catalytic, alpha (Prkaca), transcript variant 2, mRNA.
种属: Mouse
CDS区长度: 1032 (查看编码区序列)
翻译后氨基酸长度: 343 (查看氨基酸序列)
Transcript Variant: This variant (2, also known as Cs and Calpha2) contains an alternate 5'-most exon and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct and shorter N-terminus, compared to isoform 1. This variant is testis-specific and the encoded isoform does not contain the myristylation signal found in isoform 1 (PMID: 10841548 and PMID: 10982398). There are no publicly available full-length transcripts for this variant, but it is supported by publication data, including PMID: 10982398.

订购信息

产品编号 产品名称 载体 规格 价格
G134960 小鼠 Prkaca (NM_001277898) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

小鼠 Prkaca (NM_008854) cDNA克隆 transcript variant 1
小鼠 Prkaca (NM_001277898) cDNA克隆 transcript variant 2

基因简介

This gene encodes a member of the serine/threonine protein kinase family. The holoenzyme, protein kinase A (also known as cyclic-AMP dependent protein kinase), mediates cellular response to changes in cyclic-AMP levels. This gene encodes the alpha catalytic subunit of protein kinase A. Protein kinase A-mediated signaling is transduced via phosphorylation of target proteins, and is important for many cellular functions, including mammalian sperm maturation and motility. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Apr 2013]

相关产品