人 ARHGEF12 (NM_015313) cDNA克隆

Accession: NM_015313
基因名称: ARHGEF12
基因别名: LARG; PRO2792
基因描述: Homo sapiens Rho guanine nucleotide exchange factor (GEF) 12 (ARHGEF12), transcript variant 1, mRNA.
种属: Human
CDS区长度: 4635 (查看编码区序列)
翻译后氨基酸长度: 1544 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
产品编号 产品名称 载体 规格 价格
G140588 人 ARHGEF12 (NM_015313) cDNA克隆 pDONR223 2ug质粒 点击询价

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]