人 ARHGEF12 (NM_001198665) cDNA克隆

基本信息

Accession: NM_001198665
基因名称: ARHGEF12
基因别名: LARG; PRO2792
基因描述: Homo sapiens Rho guanine nucleotide exchange factor (GEF) 12 (ARHGEF12), transcript variant 2, mRNA.
种属: Human
CDS区长度: 4578 (查看编码区序列)
翻译后氨基酸长度: 1525 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G140589 人 ARHGEF12 (NM_001198665) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ARHGEF12 (NM_015313) cDNA克隆 transcript variant 1
人 ARHGEF12 (NM_001198665) cDNA克隆 transcript variant 2

基因简介

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

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