人 SIRT5 (NM_031244) cDNA克隆

基本信息

Accession: NM_031244
基因名称: SIRT5
基因别名: SIR2L5
基因描述: Homo sapiens sirtuin 5 (SIRT5), transcript variant 2, mRNA.
种属: Human
CDS区长度: 900 (查看编码区序列)
翻译后氨基酸长度: 299 (查看氨基酸序列)
Transcript Variant: This variant (2) contains a distinct 5' UTR, C-terminal coding region, and 3' UTR as compared to transcript variant 1. This variant encodes isoform 2 which has a distinct and shorter C-terminus than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G140664 人 SIRT5 (NM_031244) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SIRT5 (NM_012241) cDNA克隆 transcript variant 1
人 SIRT5 (NM_031244) cDNA克隆 transcript variant 2
人 SIRT5 (NM_001193267) cDNA克隆 transcript variant 3
人 SIRT5 (NM_001242827) cDNA克隆 transcript variant 4

基因简介

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2010]

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