人 ABL2 (NM_001136001) cDNA克隆

基本信息

Accession: NM_001136001
基因名称: ABL2
基因别名: ARG; ABLL
基因描述: Homo sapiens c-abl oncogene 2, non-receptor tyrosine kinase (ABL2), transcript variant e, mRNA.
种属: Human
CDS区长度: 1629 (查看编码区序列)
翻译后氨基酸长度: 542 (查看氨基酸序列)
Transcript Variant: This variant (e) lacks an alternate in-frame exon in the 5' coding region, and differs in the 3' coding region and 3' UTR, compared to variant b. The resulting isoform (e) has a distinct C-terminus and is shorter than isoform b.

订购信息

产品编号 产品名称 载体 规格 价格
G144864 人 ABL2 (NM_001136001) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ABL2 (NM_007314) cDNA克隆 transcript variant b
人 ABL2 (NM_005158) cDNA克隆 transcript variant c
人 ABL2 (NM_001136000) cDNA克隆 transcript variant d
人 ABL2 (NM_001136001) cDNA克隆 transcript variant e
人 ABL2 (NM_001168236) cDNA克隆 transcript variant f
人 ABL2 (NM_001168237) cDNA克隆 transcript variant g
人 ABL2 (NM_001168238) cDNA克隆 transcript variant h
人 ABL2 (NM_001168239) cDNA克隆 transcript variant i
人 ABL2 (NM_001100108) cDNA克隆 transcript variant c

基因简介

This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2009]

相关产品