人 ABL2 (NM_001168237) cDNA克隆

基本信息

Accession: NM_001168237
基因名称: ABL2
基因别名: ARG; ABLL
基因描述: Homo sapiens c-abl oncogene 2, non-receptor tyrosine kinase (ABL2), transcript variant g, mRNA.
种属: Human
CDS区长度: 3240 (查看编码区序列)
翻译后氨基酸长度: 1079 (查看氨基酸序列)
Transcript Variant: This variant (g) lacks an alternate in-frame segment in the 3' coding region, compared to variant b, resulting in an isoform (g, also known as 1BLCTS) that is shorter than isoform b.

订购信息

产品编号 产品名称 载体 规格 价格
G144869 人 ABL2 (NM_001168237) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ABL2 (NM_007314) cDNA克隆 transcript variant b
人 ABL2 (NM_005158) cDNA克隆 transcript variant c
人 ABL2 (NM_001136000) cDNA克隆 transcript variant d
人 ABL2 (NM_001136001) cDNA克隆 transcript variant e
人 ABL2 (NM_001168236) cDNA克隆 transcript variant f
人 ABL2 (NM_001168237) cDNA克隆 transcript variant g
人 ABL2 (NM_001168238) cDNA克隆 transcript variant h
人 ABL2 (NM_001168239) cDNA克隆 transcript variant i
人 ABL2 (NM_001100108) cDNA克隆 transcript variant c

基因简介

This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2009]

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