人 ASIC2 (NM_001094) cDNA克隆

基本信息

Accession: NM_001094
基因名称: ASIC2
基因别名: ACCN; BNC1; MDEG; ACCN1; BNaC1; ASIC2a; hBNaC1
基因描述: Homo sapiens acid-sensing (proton-gated) ion channel 2 (ASIC2), transcript variant MDEG1, mRNA.
种属: Human
CDS区长度: 1539 (查看编码区序列)
翻译后氨基酸长度: 512 (查看氨基酸序列)
Transcript Variant: This variant (MDEG1) uses an alternate 5'-terminal exon, compared to variant MDEG2, resulting in a shorter isoform (MDEG1) with a distinct N-terminus, compared to isoform MDEG2.

订购信息

产品编号 产品名称 载体 规格 价格
G151933 人 ASIC2 (NM_001094) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ASIC2 (NM_001094) cDNA克隆 transcript variant MDEG1
人 ASIC2 (NM_183377) cDNA克隆 transcript variant MDEG2

基因简介

This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Feb 2012]

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