人 ASIC3 (NM_004769) cDNA克隆

基本信息

Accession: NM_004769
基因名称: ASIC3
基因别名: ACCN3; TNaC1; DRASIC; SLNAC1
基因描述: Homo sapiens acid-sensing (proton-gated) ion channel 3 (ASIC3), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1596 (查看编码区序列)
翻译后氨基酸长度: 531 (查看氨基酸序列)
Transcript Variant: This variant (1) uses an alternate splice site in the 3' coding region, compared to variant 2. The resulting protein (isoform a) has a shorter and distinct C-terminus, compared to isoform b.

订购信息

产品编号 产品名称 载体 规格 价格
G167342 人 ASIC3 (NM_004769) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ASIC3 (NM_004769) cDNA克隆 transcript variant 1
人 ASIC3 (NM_020321) cDNA克隆 transcript variant 2
人 ASIC3 (NM_020322) cDNA克隆 transcript variant 3

基因简介

This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012]

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