人 CYP4F3 (NM_000896) cDNA克隆

Accession: NM_000896
基因名称: CYP4F3
基因别名: CPF3; CYP4F; LTB4H
基因描述: Homo sapiens cytochrome P450, family 4, subfamily F, polypeptide 3 (CYP4F3), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1563 (查看编码区序列)
翻译后氨基酸长度: 520 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes isoform a, which is the same length but has internal differences compared to isoform b.
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G152167 人 CYP4F3 (NM_000896) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene, CYP4F3, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts the process of inactivating and degrading leukotriene B4, a potent mediator of inflammation. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F8, is approximately 18 kb away. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]