人 ASPN (NM_017680) cDNA克隆

Accession: NM_017680
基因名称: ASPN
基因别名: OS3; PLAP1; PLAP-1; SLRR1C
基因描述: Homo sapiens asporin (ASPN), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1140 (查看编码区序列)
翻译后氨基酸长度: 379 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
产品编号 产品名称 载体 规格 价格
G155111 人 ASPN (NM_017680) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. The encoded protein may regulate chondrogenesis by inhibiting transforming growth factor-beta 1-induced gene expression in cartilage. This protein also binds collagen and calcium and may induce collagen mineralization. Polymorphisms in the aspartic acid repeat region of this gene are associated with a susceptibility to osteoarthritis. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010]