人 MAPK3 (NM_001040056) cDNA克隆

Accession: NM_001040056
基因名称: MAPK3
基因别名: ERK1; ERT2; ERK-1; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK
基因描述: Homo sapiens mitogen-activated protein kinase 3 (MAPK3), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1074 (查看编码区序列)
翻译后氨基酸长度: 357 (查看氨基酸序列)
Transcript Variant: This variant (2, also known as ERK1c) lacks several exons and its 3'-terminal exon extends past a splice site that is used in variant 1. The encoded isoform (2) has a shorter and distinct C-terminus, compared to isoform 1.
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G155509 人 MAPK3 (NM_001040056) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008]