人 TCF7L2 (NM_001146284) cDNA克隆

基本信息

Accession: NM_001146284
基因名称: TCF7L2
基因别名: TCF4; TCF-4
基因描述: Homo sapiens transcription factor 7-like 2 (T-cell specific, HMG-box) (TCF7L2), transcript variant 4, mRNA.
种属: Human
CDS区长度: 1368 (查看编码区序列)
翻译后氨基酸长度: 455 (查看氨基酸序列)
Transcript Variant: This variant (4) has multiple differences in the coding region, compared to variant 1, one of which results in a translational frameshift. The resulting protein (isoform 4) has a distinct C-terminus and is shorter than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G161412 人 TCF7L2 (NM_001146284) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TCF7L2 (NM_001146274) cDNA克隆 transcript variant 1
人 TCF7L2 (NM_001198528) cDNA克隆 transcript variant 10
人 TCF7L2 (NM_001198529) cDNA克隆 transcript variant 11
人 TCF7L2 (NM_001198530) cDNA克隆 transcript variant 12
人 TCF7L2 (NM_001198531) cDNA克隆 transcript variant 13
人 TCF7L2 (NM_030756) cDNA克隆 transcript variant 2
人 TCF7L2 (NM_001146283) cDNA克隆 transcript variant 3
人 TCF7L2 (NM_001146284) cDNA克隆 transcript variant 4
人 TCF7L2 (NM_001146285) cDNA克隆 transcript variant 5
人 TCF7L2 (NM_001146286) cDNA克隆 transcript variant 6
人 TCF7L2 (NM_001198525) cDNA克隆 transcript variant 7
人 TCF7L2 (NM_001198526) cDNA克隆 transcript variant 8
人 TCF7L2 (NM_001198527) cDNA克隆 transcript variant 9

基因简介

This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.[provided by RefSeq, Oct 2010]

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