人 TCF7L2 (NM_001198526) cDNA克隆

Accession: NM_001198526
基因名称: TCF7L2
基因别名: TCF4; TCF-4
基因描述: Homo sapiens transcription factor 7-like 2 (T-cell specific, HMG-box) (TCF7L2), transcript variant 8, mRNA.
种属: Human
CDS区长度: 1740 (查看编码区序列)
翻译后氨基酸长度: 579 (查看氨基酸序列)
Transcript Variant: This variant (8) has multiple differences in the coding region but maintains the reading frame, compared to variant 1. This variant encodes isoform 8, which is shorter than isoform 1.
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G161420 人 TCF7L2 (NM_001198526) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.[provided by RefSeq, Oct 2010]