人 TRPC3 (NM_003305) cDNA克隆

Accession: NM_003305
基因名称: TRPC3
基因别名: TRP3
基因描述: Homo sapiens transient receptor potential cation channel, subfamily C, member 3 (TRPC3), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2547 (查看编码区序列)
翻译后氨基酸长度: 848 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an upstream exon , compared to variant 1, resulting in a different 5' UTR and 5' coding region and translation initiation from an inframe, downstream ATG. The encoded protein (isoform b) has a shorter N-terminus, compared to isoform a.
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G162770 人 TRPC3 (NM_003305) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]