人 CASP8AP2 (NM_001137668) cDNA克隆

基本信息

Accession: NM_001137668
基因名称: CASP8AP2
基因别名: CED-4; FLASH; RIP25
基因描述: Homo sapiens caspase 8 associated protein 2 (CASP8AP2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 5949 (查看编码区序列)
翻译后氨基酸长度: 1982 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1.

订购信息

产品编号 产品名称 载体 规格 价格
G168128 人 CASP8AP2 (NM_001137668) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CASP8AP2 (NM_012115) cDNA克隆 transcript variant 1
人 CASP8AP2 (NM_001137667) cDNA克隆 transcript variant 2
人 CASP8AP2 (NM_001137668) cDNA克隆 transcript variant 3

基因简介

This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Nov 2008]

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