小鼠 Abca1 (NM_013454) cDNA克隆

Accession: NM_013454
基因名称: Abca1
基因别名: Abc1; ABC-1
基因描述: Mus musculus ATP-binding cassette, sub-family A (ABC1), member 1 (Abca1), mRNA.
种属: Mouse
CDS区长度: 6786 (查看编码区序列)
翻译后氨基酸长度: 2261 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G168257 小鼠 Abca1 (NM_013454) cDNA克隆 pDONR223 2ug质粒 点击询价

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. In humans, this protein functions as a cholesterol efflux pump in the cellular lipid removal pathway. Mutations in the human gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency. [provided by RefSeq, Jul 2008]