小鼠 Abca4 (NM_007378) cDNA克隆

Accession: NM_007378
基因名称: Abca4
基因别名: RmP; Abcr; Abc10; AW050280; D430003I15Rik
基因描述: Mus musculus ATP-binding cassette, sub-family A (ABC1), member 4 (Abca4), mRNA.
种属: Mouse
CDS区长度: 6933 (查看编码区序列)
翻译后氨基酸长度: 2310 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G168258 小鼠 Abca4 (NM_007378) cDNA克隆 pDONR223 2ug质粒 点击询价

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein was the first of the ABC transporters to be observed in photoreceptors and may play a role in the photoresponse. Mutations in the human gene are found in patients diagnosed with Stargardt disease and are associated with retinitis pigmentosa-19 and macular degeneration age-related 2. [provided by RefSeq, Jul 2008]