人 NLRC3 (NM_178844) cDNA克隆

Accession: NM_178844
基因名称: NLRC3
基因别名: NOD3; CLR16.2
基因描述: Homo sapiens NLR family, CARD domain containing 3 (NLRC3), transcript variant 1, mRNA.
种属: Human
CDS区长度: 3198 (查看编码区序列)
翻译后氨基酸长度: 1065 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the protein.
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G170781 人 NLRC3 (NM_178844) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a NOD-like receptor family member. The encoded protein is a cytosolic regulator of innate immunity. This protein directly interacts with stimulator of interferon genes (STING), to prevent its proper trafficking, resulting in disruption of STING-dependent activation of the innate immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]